The Neurobiology of Anorexia Nervosa and Abnormal Reward Learning Processes: A Systematic Review

Abstract
 Objective: Given the array of neuroimaging studies examining neurobiology anorexia nervosa, purpose this paper was to further highlight localized neurobiological abnormalities when reward learning pathways in patients suffering from AN.
 Methods: Literature searches using PsycINFO, EMBASE, and MEDLINE were conducted March 2022 search terms relating AN, learning, neuroimaging. Relevant that included must be written English, have at least one clinical sample either acute and/or recovered adult adolescent female with controlled a healthy control group, published peer-reviewed journal, containing component.
 Results: For systematic review, 20 relevant elucidate brain regional functional differences respect individuals AN compared controls. These include dopamine neuron cortisol release relation dopaminergic pathways, as well involved subconstructs expectancies, punishment sensitivity, social reward, body dissatisfaction image distortion.
 Conclusion: In across construct, research efforts focus on these important might help inform development new interventions aimed particular pathways.